Novodiax

CoNAb™ SARS-CoV-2 Neutralizing Antibody POC Test Kit

A rapid point of care test for qualitative assessment of neutralizing antibodies to SARS-CoV-2 (virus responsible for COVID-19) in human blood, plasma, and serum. Currently available for research use only.

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CoNAb POC Lateral Flow Test Strip

How It Works

The CoNAb Test Kit is a lateral flow test intended for qualitative detection of neutralizing antibodies (NAb) to SARS-CoV-2 in human blood, plasma or serum.

This test assays for the inhibition of the SARS-CoV-2 spike protein S1 subunit—which is conjugated to a sensitive tag and gold nanoparticles (GNP) using our proprietary technology—binding to the ACE receptor.

Results are available in as little as 15 minutes, enabling rapid decision making.

Why a Neutralizing Antibody Test?

“We’re excited to offer this new test for SARS-CoV-2 neutralizing antibodies that we envision providing critical information to aid in screening plasma donors, evaluating the effectiveness of COVID-19 vaccines, and more—which will only increase in importance as new variants of the virus emerge over the coming years.”

Jin Wu, Ph.D., Vice President of Innovation, Novodiax

Test (T) Line Shows Relative Inhibition of Individual’s Neutralizing Antibodies

Easy Interpretation

The CoNAb Test Kit provides a reference of the amount of NAb present at 1:10 dilution in whole blood (equivalent to 1:20 diluted serum or plasma). Featuring a user-friendly design that presents a built-in Control (C) line as well as a Test (T) line indicating the level of NAb inhibition in your sample.

Reliable Performance

Using 48 COVID-19 patient samples (1:12 dilution)–purchased from an independent Biobank–we observed 85.71% concordance with gold-standard RT-PCR, 72.92% sensitivity, and 97% specificity.

Performance results of CoNAb Test Kit

Post Vaccination CoNAb Test Inhibition.

Convenient All-in-one Kit

The CoNAb Test Kit contains the following items, making sample collection and testing both simple and convenient:

  • CoNAb Lateral Flow Test Device (1), sample buffer (1ml) micro dispenser (1), spring loaded 26 Gauge lancet (1), capillary blood transfer pipet (10μl) (1), alcohol pad (1), desiccant bag (1g) (1), Instruction for Use document (1)

Reference Publications

  • Lau, E. H. Y.et al. Neutralizing antibody titres in SARS-CoV-2 infections. Nature Communications12, 63, doi:10.1038/s41467-020-20247-4 (2021).
  • Mulligan, M. J.et al.PhaseI/II study of COVID-19 RNA vaccine BNT162b1 in adults. Nature586, 589-593, doi:10.1038/s41586-020-2639-4 (2020).
  • Jackson, L. A.et al.An mRNA Vaccine against SARS-CoV-2 —Preliminary Report. New England Journal of Medicine383, 1920-1931, doi:10.1056/NEJMoa2022483 (2020).

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If you would like to speak to an expert about the CoNAb Test Kit or acquire the RUO version for early evaluation and/or use, please complete the form below.